Endosalpingiosis is the presence of ectopic, cystic glands outside the fallopian tube that are lined with fallopian tube-type ciliated epithelium. Endosalpingiosis may occur in pelvic organs, including ovaries, fallopian tube serosa, uterine serosa, myometrium, or pelvic peritoneum. It may also occur in the bladder or in a retroperitoneal or axillary lymph node. Thousands of women are undiagnosed or misdiagnosed with this disease everyday and we need to change that list. Endosalpingiosis is similar to Endometriosis the same symptoms. Like the uterine endometrial of Endometriosis, estrogen can cause salpingoitic tissues outside of the fallopian tubes to grow and potentially aggravate the surrounding areas. High levels cause the glandular tissues to proliferate and, especially important, they cause the number of and activity of ciliated epithelial cells (that would normally line the fallopian tubes) to increase. This disease is so rare that it does not appear on the national rare disease list. With time and support from doctors and the community we need to make sure that everyone understands how this disease is affecting women and provide the necessary treatment and support.
Endosalpingiosis is diagnosed by a pathologist on excision (e.g. biopsy) with a surgery. It is characterized by cysts with tubal-type epithelium surrounded by a fibrous stroma. It is not often associated with hemorrhage. A tubal-type epithelium surrounded by endometrial-type stroma is a variant of endometriosis, not endosalpingiosis. Other problems caused by this condition such as ovarian cysts, chocolate cysts, fertility, pelvic pain, adhesions arise depending on the case.